Title : Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization.

Pub. Date : 2006 May

PMID : 16543952






3 Functional Relationships(s)
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1 Our data support the model that during podocyte intercellular junction formation, engagement of the nephrin ectodomain induces transient Fyn catalytic activity that results in nephrin phosphorylation on specific nephrin cytoplasmic domain tyrosine residues. Tyrosine NPHS1 adhesion molecule, nephrin Homo sapiens
2 Our data support the model that during podocyte intercellular junction formation, engagement of the nephrin ectodomain induces transient Fyn catalytic activity that results in nephrin phosphorylation on specific nephrin cytoplasmic domain tyrosine residues. Tyrosine NPHS1 adhesion molecule, nephrin Homo sapiens
3 Our data support the model that during podocyte intercellular junction formation, engagement of the nephrin ectodomain induces transient Fyn catalytic activity that results in nephrin phosphorylation on specific nephrin cytoplasmic domain tyrosine residues. Tyrosine NPHS1 adhesion molecule, nephrin Homo sapiens