Pub. Date : 2006 May 5
PMID : 16527810
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Roles of the mammalian cytosolic cysteine desulfurase, ISCS, and scaffold protein, ISCU, in iron-sulfur cluster assembly. | Iron | iron-sulfur cluster assembly enzyme | Homo sapiens |
| 2 | When incubated with iron regulatory protein 1, cysteine, and iron, the cytosolic forms of ISCS and ISCU facilitated efficient formation of a [4Fe-4S] cluster on IRP1. | Iron | iron-sulfur cluster assembly enzyme | Homo sapiens |
| 3 | Thus, the cytosolic form of ISCS is a functional cysteine desulfurase that can collaborate with cytosolic ISCU to promote de novo iron-sulfur cluster formation. | Iron | iron-sulfur cluster assembly enzyme | Homo sapiens |