Title : Relationship between therapeutic efficacy of arterial infusion chemotherapy and expression of P-glycoprotein and p53 protein in advanced hepatocellular carcinoma.

Pub. Date : 2006 Feb 14

PMID : 16521213






2 Functional Relationships(s)
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1 When only the data from the 11 patients treated with anthraquinone drug, mitoxantrone, were analyzed, however, the number of patients who showed poor response to treatment was significantly higher among the p53-positive patients (P=0.012), irrespective of the survival outcome. Anthraquinones tumor protein p53 Homo sapiens
2 Similarly, immunostaining to evaluate p53 protein may be useful to predict the response in patients treated with an anthraquinone drug. Anthraquinones tumor protein p53 Homo sapiens