Pub. Date : 2006 Apr 21
PMID : 16516150
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Histone deacetylase inhibitor apicidin induces cyclin E expression through Sp1 sites. | apicidin | histone deacetylase 9 | Homo sapiens |
| 2 | We show that a histone deacetylase (HDAC) inhibitor apicidin increases the transcriptional activity of cyclin E gene, which results in accumulation of cyclin E mRNA and protein in a time- and dose-dependent manner. | apicidin | histone deacetylase 9 | Homo sapiens |
| 3 | We show that a histone deacetylase (HDAC) inhibitor apicidin increases the transcriptional activity of cyclin E gene, which results in accumulation of cyclin E mRNA and protein in a time- and dose-dependent manner. | apicidin | histone deacetylase 9 | Homo sapiens |
| 4 | Our results demonstrate that regulation of histone modification by an HDAC inhibitor apicidin contributes to induction of cyclin E expression and this effect is Sp1-dependent. | apicidin | histone deacetylase 9 | Homo sapiens |