Title : Effects of chronic renal failure on the pharmacokinetics of ruboxistaurin and its active metabolite 338522.

Pub. Date : 2006

PMID : 16509761






1 Functional Relationships(s)
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1 BACKGROUND: Ruboxistaurin, a specific inhibitor of the beta(1) and beta(2) isoforms of protein kinase C, is currently in clinical development for the treatment of several diabetic microvascular complications. ruboxistaurin potassium calcium-activated channel subfamily M regulatory beta subunit 1 Homo sapiens