Title : Flavopiridol in patients with relapsed or refractory multiple myeloma: a phase 2 trial with clinical and pharmacodynamic end-points.

Pub. Date : 2006 Mar

PMID : 16503551






1 Functional Relationships(s)
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Protein Name
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1 Flavopiridol downregulates anti-apoptotic regulators including Mcl-1, upregulates p53, globally attenuates transcription through inhibition of P-TEFb, binds to DNA, and inhibits angiogenesis. alvocidib tumor protein p53 Homo sapiens