Pub. Date : 2005 Dec
PMID : 16503324
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND: Metformin hydrochloride is widely used for the treatment of type 2 diabetes mellitus (DM-2). | Metformin | immunoglobulin heavy diversity 1-14 (non-functional) | Homo sapiens |
| 2 | OBJECTIVE: The aim of this article was to report a case of serious hepatotoxicity possibly associated with metformin use in an elderly patient with DM-2. | Metformin | immunoglobulin heavy diversity 1-14 (non-functional) | Homo sapiens |
| 3 | METHODS: After receiving metformin 500 mg/d for 3 weeks, a 73-year-old Japanese woman weighing 33.5 kg with poorly controlled DM-2 presented with fatigue, jaundice, nausea, vomiting, anorexia, and abdominal pain. | Metformin | immunoglobulin heavy diversity 1-14 (non-functional) | Homo sapiens |
| 4 | CONCLUSIONS: In this case of an elderly woman with DM-2 who presented with symptoms of hepatotoxicity after 3 weeks of metformin treatment, metformin appeared to have caused a mixed-type (hepatocellular and cholestatic) hepatic damage. | Metformin | immunoglobulin heavy diversity 1-14 (non-functional) | Homo sapiens |
| 5 | CONCLUSIONS: In this case of an elderly woman with DM-2 who presented with symptoms of hepatotoxicity after 3 weeks of metformin treatment, metformin appeared to have caused a mixed-type (hepatocellular and cholestatic) hepatic damage. | Metformin | immunoglobulin heavy diversity 1-14 (non-functional) | Homo sapiens |