Title : Hyperoxia stimulates an Nrf2-ARE transcriptional response via ROS-EGFR-PI3K-Akt/ERK MAP kinase signaling in pulmonary epithelial cells.

Pub. Date : 2006 Jan-Feb

PMID : 16487036






1 Functional Relationships(s)
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1 Likewise, the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, AG1478, blocked hyperoxia-stimulated Akt and ERK1/2 phosphorylation, Nrf2 nuclear accumulation, and ARE-driven transcription. RTKI cpd mitogen-activated protein kinase 3 Mus musculus