Title : Dual specificity of the interfacial inhibitor brefeldin a for arf proteins and sec7 domains.

Pub. Date : 2006 Apr 28

PMID : 16484231






2 Functional Relationships(s)
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1 A single Phe/Tyr substitution is sufficient to achieve BFA sensitivity of the Sec7 domain, which is supported by our characterization of brefeldin C (BFC), a BFA analog that cannot interact with the Tyr residue, and by free energy computations. brefeldin C cytohesin 1 Homo sapiens
2 A single Phe/Tyr substitution is sufficient to achieve BFA sensitivity of the Sec7 domain, which is supported by our characterization of brefeldin C (BFC), a BFA analog that cannot interact with the Tyr residue, and by free energy computations. brefeldin C cytohesin 1 Homo sapiens