Title : Vitamin A improves Pax3 expression that is decreased in the heart of rats with experimental diaphragmatic hernia.

Pub. Date : 2006 Feb

PMID : 16481245






3 Functional Relationships(s)
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1 The aims of this study were to examine whether Pax3 expression is decreased in the heart of E13 E15 and E21 rats exposed to nitrofen and if vitamin A reverts this effect. nitrofen paired box 3 Rattus norvegicus
2 RESULTS: Pax3 mRNA expression was significantly decreased on E13 and E15 in the hearts of nitrofen-treated embryos and it remained decreased although not significantly on E21. nitrofen paired box 3 Rattus norvegicus
3 CONCLUSIONS: Pax3 is underexpressed in the hearts of nitrofen exposed embryonal rats on days 13th and 15th of gestation and tends to be lower than normal near term. nitrofen paired box 3 Rattus norvegicus