Pub. Date : 2005 May-Jun
PMID : 16437946
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Two different studies were performed: the first was carried out to analyze the doxorubicin-TNFalpha-hyperthermia association (three different trials) in terms of toxicity and efficacy of the treatment (tumor response, locoregional control, disease free and overall survival). | Doxorubicin | tumor necrosis factor | Homo sapiens |
2 | The results showed that the trimodality association (doxorubicin TNFalpha and hyperthermia) is the best regimen able to obtain a 77% of objective response and 77% of limb sparing in patients candidate to amputation but may result in high local toxicity if high temperatures (>41.5 degrees C) were maintained during perfusion. | Doxorubicin | tumor necrosis factor | Homo sapiens |