Title : Snf1-dependent and Snf1-independent pathways of constitutive ADH2 expression in Saccharomyces cerevisiae.

Pub. Date : 2006 Apr

PMID : 16415371






3 Functional Relationships(s)
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1 The transcription factor Adr1 directly activates the expression of genes encoding enzymes in numerous pathways that are upregulated after the exhaustion of glucose in the yeast Saccharomyces cerevisiae. Glucose DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C
2 ADH2, encoding the alcohol dehydrogenase isozyme required for ethanol oxidation, is a highly glucose-repressed, Adr1-dependent gene. Glucose DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C
3 Using a genetic screen we isolated >100 mutants in 12 complementation groups that exhibit ADR1-dependent constitutive ADH2 expression on glucose. Glucose DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C