Title : p21CDKN1A allows the repair of replication-mediated DNA double-strand breaks induced by topoisomerase I and is inactivated by the checkpoint kinase inhibitor 7-hydroxystaurosporine.

Pub. Date : 2006 May 11

PMID : 16407843






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In human colon carcinoma HCT116 cells with wild-type (wt) p53, gammaH2AX reverses after camptothecin removal. gammah2ax tumor protein p53 Homo sapiens