Pub. Date : 2006 May 11
PMID : 16407843
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We report that defects of p21(CDKN1A) and p53 enhance camptothecin-induced histone H2AX phosphorylation (gammaH2AX), a marker for DNA DSBs. | Camptothecin | tumor protein p53 | Homo sapiens |
2 | In human colon carcinoma HCT116 cells with wild-type (wt) p53, gammaH2AX reverses after camptothecin removal. | Camptothecin | tumor protein p53 | Homo sapiens |