Title : GG: a domain involved in phage LTF apparatus and implicated in human MEB and non-syndromic hearing loss diseases.

Pub. Date : 2006 Jan 23

PMID : 16406369






1 Functional Relationships(s)
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1 Here, we report the identification of a novel domain--GG (domain in KIAA1199, FAM3, POMGnT1 and Tmem2 proteins, with two well-conserved glycine residues), present in eukaryotic FAM3 superfamily (FAM3A, FAM3B, FAM3C and FAM3D), POMGnT1 (protein O-linked mannose beta-1,2-N-acetylglucosaminyltransferase), TEM2 proteins as well as phage gp35 proteins. Glycine FAM3 metabolism regulating signaling molecule D Homo sapiens