Title : Gender differences and effects of sex steroids and dehydroepiandrosterone on androgen and oestrogen alpha receptors in mouse sebaceous glands.

Pub. Date : 2006 Jan

PMID : 16403089






3 Functional Relationships(s)
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1 Treatment of GDX animals with dihydrotestosterone (DHT) or dehydroepiandrosterone (DHEA) increases AR expression, while 17beta-estradiol (E2) decreases the stimulatory effect of DHT and DHEA. Dehydroepiandrosterone androgen receptor Mus musculus
2 Treatment of GDX animals with dihydrotestosterone (DHT) or dehydroepiandrosterone (DHEA) increases AR expression, while 17beta-estradiol (E2) decreases the stimulatory effect of DHT and DHEA. Dehydroepiandrosterone androgen receptor Mus musculus
3 CONCLUSIONS: The present data show gender differences and demonstrate that DHT, E2 and DHEA exert specific effects on the expression of AR and ERalpha in mouse sebocytes. Dehydroepiandrosterone androgen receptor Mus musculus