Pub. Date : 2006 May 15
PMID : 16380993
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Selenium can disrupt the androgen pathway, which has been implicated in modulating SELENBP1 expression. | Selenium | selenium binding protein 1 | Homo sapiens |
| 2 | Interestingly, SELENBP1 mRNA and protein levels were reduced by androgen and elevated by selenium treatment in the normal HOSE cells, whereas reversed responses were observed in the ovarian cancer cell lines. | Selenium | selenium binding protein 1 | Homo sapiens |
| 3 | These results suggest that changes of SELENBP1 expression in malignant ovarian cancer are an indicator of aberration of selenium/androgen pathways and may reveal prognostic information of ovarian cancer. | Selenium | selenium binding protein 1 | Homo sapiens |