Title : Relaxation and cyclic GMP levels in response to sildenafil in human pulmonary arteries from donors.

Pub. Date : 2006 Jan 20

PMID : 16380114






3 Functional Relationships(s)
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1 Relaxation and cyclic GMP levels in response to sildenafil in human pulmonary arteries from donors. Sildenafil Citrate 5'-nucleotidase, cytosolic II Homo sapiens
2 SNP (10(-7) M) caused elevation of cyclic GMP levels that was potentiated by sildenafil (10(-6) M). Sildenafil Citrate 5'-nucleotidase, cytosolic II Homo sapiens
3 Thus, the enhancement of SNP-induced relaxation by sildenafil is mainly due to an increase in cyclic GMP accumulation. Sildenafil Citrate 5'-nucleotidase, cytosolic II Homo sapiens