Title : Autocrine stimulation of growth of AR4-2J rat pancreatic tumour cells by gastrin.

Pub. Date : 1992 Jul

PMID : 1637673






1 Functional Relationships(s)
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1 In contrast, the IC50 for inhibition of cell growth with two benzodiazepine-derived antagonists, the CCK-B receptor antagonist L-365,260 (4.6 x 10(-5) M) and the CCK-A receptor antagonist devazepide (1.7 x 10(-5) M) were two-three orders of magnitude greater than those required to inhibit gastrin binding (10(-8)-10(-7) M). l-365 cholecystokinin B receptor Rattus norvegicus