Title : Scoparone inhibits PMA-induced IL-8 and MCP-1 production through suppression of NF-kappaB activation in U937 cells.

Pub. Date : 2006 May 15

PMID : 16376386






5 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Scoparone inhibits PMA-induced IL-8 and MCP-1 production through suppression of NF-kappaB activation in U937 cells. scoparone C-X-C motif chemokine ligand 8 Homo sapiens
2 In this study, the effects of scoparone on the expression of interleukin-8 (IL-8) and monocyte chemotactic protein-1 (MCP-1) and activation of nuclear factor-kappaB (NF-kappaB) were examined in U937 human monocytes activated with phorbol 12-myristate 13-acetate (PMA). scoparone C-X-C motif chemokine ligand 8 Homo sapiens
3 In this study, the effects of scoparone on the expression of interleukin-8 (IL-8) and monocyte chemotactic protein-1 (MCP-1) and activation of nuclear factor-kappaB (NF-kappaB) were examined in U937 human monocytes activated with phorbol 12-myristate 13-acetate (PMA). scoparone C-X-C motif chemokine ligand 8 Homo sapiens
4 Scoparone concentration-dependently reduced the release of IL-8 and MCP-1 protein and expression of IL-8 and MCP-1 mRNA levels induced by PMA. scoparone C-X-C motif chemokine ligand 8 Homo sapiens
5 Scoparone concentration-dependently reduced the release of IL-8 and MCP-1 protein and expression of IL-8 and MCP-1 mRNA levels induced by PMA. scoparone C-X-C motif chemokine ligand 8 Homo sapiens