Pub. Date : 2005 Dec
PMID : 16372404
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Bistramide A has been reported to selectively activate protein kinase C (PKC) delta, leading to the view that PKCdelta is the principal mediator of antiproliferative activity of this natural product. | bistratene A | protein kinase C delta | Homo sapiens |
2 | Bistramide A has been reported to selectively activate protein kinase C (PKC) delta, leading to the view that PKCdelta is the principal mediator of antiproliferative activity of this natural product. | bistratene A | protein kinase C delta | Homo sapiens |
3 | Contrary to this observation, we established that bistramide A binds PKCdelta with low affinity, does not activate this kinase in vitro and does not translocate GFP-PKCdelta. | bistratene A | protein kinase C delta | Homo sapiens |