Title : Actin is the primary cellular receptor of bistramide A.

Pub. Date : 2005 Dec

PMID : 16372404






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Bistramide A has been reported to selectively activate protein kinase C (PKC) delta, leading to the view that PKCdelta is the principal mediator of antiproliferative activity of this natural product. bistratene A protein kinase C delta Homo sapiens
2 Bistramide A has been reported to selectively activate protein kinase C (PKC) delta, leading to the view that PKCdelta is the principal mediator of antiproliferative activity of this natural product. bistratene A protein kinase C delta Homo sapiens
3 Contrary to this observation, we established that bistramide A binds PKCdelta with low affinity, does not activate this kinase in vitro and does not translocate GFP-PKCdelta. bistratene A protein kinase C delta Homo sapiens