Pub. Date : 2006 Feb 17
PMID : 16365037
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Methenyltetrahydrofolate synthetase (MTHFS) is the only enzyme that metabolizes 5-formylTHF and catalyzes its ATP-dependent conversion to 5,10-methenylTHF. | Leucovorin | methenyltetrahydrofolate synthetase | Homo sapiens |
| 2 | Methenyltetrahydrofolate synthetase (MTHFS) is the only enzyme that metabolizes 5-formylTHF and catalyzes its ATP-dependent conversion to 5,10-methenylTHF. | Leucovorin | methenyltetrahydrofolate synthetase | Homo sapiens |
| 3 | Feedback metabolic regulation of MTHFS by 10-formylTHF indicates that 5-formylTHF can only accumulate in the presence of 10-formylTHF, providing the first evidence that 5-formylTHF is a storage form of excess formylated folates in mammalian cells. | Leucovorin | methenyltetrahydrofolate synthetase | Homo sapiens |
| 4 | Feedback metabolic regulation of MTHFS by 10-formylTHF indicates that 5-formylTHF can only accumulate in the presence of 10-formylTHF, providing the first evidence that 5-formylTHF is a storage form of excess formylated folates in mammalian cells. | Leucovorin | methenyltetrahydrofolate synthetase | Homo sapiens |