Title : Overexpression of thymosin beta-4 renders SW480 colon carcinoma cells more resistant to apoptosis triggered by FasL and two topoisomerase II inhibitors via downregulating Fas and upregulating Survivin expression, respectively.

Pub. Date : 2006 May

PMID : 16364925






1 Functional Relationships(s)
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1 On the other hand, pretreating these cells with an MMP inhibitor restored not only their Fas levels but also their sensitivity to CH-11, suggesting a pivotal role of MMP in downregulating Fas in Tbeta4 overexpressers. 4-dimethylamino-3',4'-dimethoxychalcone thymosin beta 4 X-linked Homo sapiens