Title : Effects of retigabine on the neurodegeneration and extracellular glutamate changes induced by 4-aminopyridine in rat hippocampus in vivo.

Pub. Date : 2005 Dec

PMID : 16362775






1 Functional Relationships(s)
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1 Retigabine is an opener of the KCNQ2/Q3-type K+ channel that possesses antiepileptic action and may be neuroprotective, and we have therefore studied its effect on the hyperexcitation, the neuronal damage and the changes in extracellular glutamate induced by 4-AP. ezogabine potassium voltage-gated channel subfamily Q member 2 Rattus norvegicus