Title : New phenotypes of functional expression of the mKir2.1 channel in potassium efflux-deficient Saccharomyces cerevisiae strains.

Pub. Date : 2005 Dec

PMID : 16358319






3 Functional Relationships(s)
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1 The use of a mutant strain lacking both potassium efflux and uptake transporters (ena1-4delta nha1delta trk1delta trk2delta) enabled the monitoring of channel activity on two levels--the provision of the necessary amount of intracellular K+ in media with low potassium concentrations, and simultaneously, the channel"s contribution to cell potassium sensitivity in the presence of high external K+. Potassium Trk1p Saccharomyces cerevisiae S288C
2 The use of a mutant strain lacking both potassium efflux and uptake transporters (ena1-4delta nha1delta trk1delta trk2delta) enabled the monitoring of channel activity on two levels--the provision of the necessary amount of intracellular K+ in media with low potassium concentrations, and simultaneously, the channel"s contribution to cell potassium sensitivity in the presence of high external K+. Potassium Trk1p Saccharomyces cerevisiae S288C
3 The use of a mutant strain lacking both potassium efflux and uptake transporters (ena1-4delta nha1delta trk1delta trk2delta) enabled the monitoring of channel activity on two levels--the provision of the necessary amount of intracellular K+ in media with low potassium concentrations, and simultaneously, the channel"s contribution to cell potassium sensitivity in the presence of high external K+. Potassium Trk1p Saccharomyces cerevisiae S288C