Title : Glycogen synthase kinase-3 phosphorylation, T-cell factor signaling activation, and cell morphology change following stimulation of thromboxane receptor alpha.

Pub. Date : 2006 Apr

PMID : 16352701






1 Functional Relationships(s)
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Protein Name
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1 N-[2-(4-Bromocinnamylamino)ethyl]-5-isoquinoline (H89), a protein kinase A (PKA) inhibitor, totally blocked the phosphorylation of GSK-3, whereas wortmannin, a phosphatidylinositol 3-kinase (PI-3 kinase) inhibitor, partially attenuated it, suggesting that PKA as well as PI-3 kinase/Akt pathway were involved in TP-induced phosphorylation of GSK-3. n-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline AKT serine/threonine kinase 1 Homo sapiens