Title : Base treatment corrects defects due to misfolding of mutant cystic fibrosis transmembrane conductance regulator.

Pub. Date : 2005 Dec

PMID : 16344066






1 Functional Relationships(s)
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1 BACKGROUND & AIMS: The most common form of the disease-causing cystic fibrosis transmembrane conductance regulator mutation, DeltaF508, leads to a misfolded protein that undergoes endoplasmic reticulum-associated degradation. Adenosine Monophosphate CF transmembrane conductance regulator Homo sapiens