Title : Involvement of mitogen-activated protein kinase and NF-kappaB activation in Ca2+-induced IL-8 production in human mast cells.

Pub. Date : 2005 Dec 7

PMID : 16343928






1 Functional Relationships(s)
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1 Pretreatment of MAPK inhibitors (PD98059 and SB203580) markedly blocked Ca(2+)-induced IL-8 production from cells, and anti-inflammatory drugs, such as dexamethasone and cyclosporin A, partially inhibited the activation of ERK1/2. SB 203580 C-X-C motif chemokine ligand 8 Homo sapiens