Pub. Date : 2006 Jan
PMID : 16340664
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Endothelin-1 in vitro can inhibit sodium or water transport in the collecting duct and thick ascending limb through autocrine pathways. | Sodium | endothelin 1 | Mus musculus |
| 2 | Mice with collecting duct-specific knockout of the endothelin-1 gene have impaired sodium excretion in response to sodium loading and have hypertension which worsens with high salt intake. | Sodium | endothelin 1 | Mus musculus |
| 3 | Mice with collecting duct-specific knockout of the endothelin-1 gene have impaired sodium excretion in response to sodium loading and have hypertension which worsens with high salt intake. | Sodium | endothelin 1 | Mus musculus |
| 4 | SUMMARY: Medullary endothelin-1 regulates renal sodium and water transport and medullary blood flow. | Sodium | endothelin 1 | Mus musculus |
| 5 | Medullary endothelin-1 is fundamentally important in physiologic regulation of renal sodium and water excretion and maintenance of normal systemic blood pressure. | Sodium | endothelin 1 | Mus musculus |