Title : Cytotoxic and mutagenic effects of tobacco-borne free fatty acids.

Pub. Date : 2006 Jan 1

PMID : 16337890






1 Functional Relationships(s)
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1 Furthermore, the combination of free fatty acid and iron is highly mutagenic, inducing almost as many selectable mutations in the gene for hypoxanthine/guanine phosphoribosyl transferase as does benzo[a]pyrenediolepoxide, a class I carcinogen generated from benzo[a]pyrene present in cigarette smoke. Iron hypoxanthine-guanine phosphoribosyltransferase Nicotiana tabacum