Pub. Date : 2005 Nov
PMID : 16324248
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | OBJECTIVE: To explore the effect of estradiol benzoate on the expressions of heat shock protein (HSP) 70, 90 in endometrial glandular epithelial cell. | estradiol 3-benzoate | heat shock protein family A (Hsp70) member 4 | Homo sapiens |
| 2 | The dose- and time-related effect of estradiol benzoate and ICI 182780 on the cell growth was measured by mononuclear cell direct cytotoxicity assay (methyl thiazolyl tetrazolium assay), and that on the expression of HSP70 and HSP90 in normal endometrial glandular epithelial cell in vitro was measured by immunohistochemical analysis and computerized image analysis system. | estradiol 3-benzoate | heat shock protein family A (Hsp70) member 4 | Homo sapiens |
| 3 | Estradiol benzoate treatment resulted in a time- and dose-dependent increase of the expression of HSP90 and decrease of HSP70 in human endometrial glandular epithelial cell. | estradiol 3-benzoate | heat shock protein family A (Hsp70) member 4 | Homo sapiens |
| 4 | The expression of HSP70 in 10(-9), 10(-8), 10(-7), 10(-6) mol/L estradiol benzoate for 24 hours were (38.4 +/- 5.7)%, (35.3 +/- 4.9)%, (32.5 +/- 3.1)%, (25.3 +/- 6.2)%, which were significantly lower than that of the control. | estradiol 3-benzoate | heat shock protein family A (Hsp70) member 4 | Homo sapiens |
| 5 | The estradiol benzoate-induced effects on HSP70 levels were not attenuated by the antiestrogen ICI 182780. | estradiol 3-benzoate | heat shock protein family A (Hsp70) member 4 | Homo sapiens |