Title : [Effect of neferine on the chemotherapic sensitivity of STI 571 to K562/A02 cells].

Pub. Date : 2005 Oct

PMID : 16320588






1 Functional Relationships(s)
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1 After treating with STI571 combined with neferine, the synergistic interaction on K562/A02 cells increased 4.38 folds (P < 0.05); the mdrl mRNA expression by semi-quantitative RT-PCR was significantly reduced by (45.4 +/- 2.5) % (P < 0.01); and the P-gp expression by Western blot was deregulated by 40.58% (P < 0.05). neferine phosphoglycolate phosphatase Homo sapiens