Title : Glycyrrhetinic acid and related compounds induce G1 arrest and apoptosis in human hepatocellular carcinoma HepG2.

Pub. Date : 2005 Nov-Dec

PMID : 16309197






1 Functional Relationships(s)
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1 Western blot analysis indicated that the induction of apoptosis by GA and ursolic acid was accompanied with an activation of caspase-8 and a reduction in the anti-apoptotic proteins, Bcl-2 and Bcl-xL, although the pro-apoptotic proteins, Bax and Bak, remained unaffected. ursolic acid BCL2 associated X, apoptosis regulator Homo sapiens