Title : Synchronized network activity in developing rat hippocampus involves regional hyperpolarization-activated cyclic nucleotide-gated (HCN) channel function.

Pub. Date : 2005 Nov

PMID : 16307610






2 Functional Relationships(s)
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1 Here we focus on HCN1, the prevalent HCN channel isoform in neonatal hippocampus, and demonstrate an HCN1 spatiotemporal expression pattern in both CA3 principal cells and interneurons that correlates with the developmental profile of GDPs. gdps carbonic anhydrase 3 Rattus norvegicus
2 Furthermore, ZD7288 specifically abolishes spontaneous bursting of the CA3 pyramidal cells at frequencies typical of GDPs without major influence on interneuronal firing. gdps carbonic anhydrase 3 Rattus norvegicus