Title : 1H and 13C-NMR and molecular dynamics studies of cyclosporin a interacting with magnesium(II) or cerium(III) in acetonitrile. Conformational changes and cis-trans conversion of peptide bonds.

Pub. Date : 2006 Feb 15

PMID : 16299069






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In the complex with its target (Cyp), CsA adopts a conformation with all trans peptide bonds and this feature is very important for its pharmacological action. Cyclosporine peptidylprolyl isomerase G Homo sapiens