Title : hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-gamma agonists.

Pub. Date : 2006 Jan

PMID : 16291834






1 Functional Relationships(s)
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1 PPAR-gamma agonists also activated c-met receptor tyrosine phosphorylation, induced Smad transcriptional co-repressor TG-interacting factor expression, and blocked TGF-beta/Smad-mediated gene transcription in mesangial cells. Tyrosine MET proto-oncogene, receptor tyrosine kinase Homo sapiens