Pub. Date : 2006 Jan 20
PMID : 16291740
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Mechanistically, we showed that conversion of a minimal four of these lysines to alanines but not arginines mimics p300-mediated p53 nuclear export, and these lysine-neutralizing mutations effectively prevent p53 tetramerization, thus exposing the oligomerization-regulated nuclear export signal. | Alanine | tumor protein p53 | Homo sapiens |
2 | Mechanistically, we showed that conversion of a minimal four of these lysines to alanines but not arginines mimics p300-mediated p53 nuclear export, and these lysine-neutralizing mutations effectively prevent p53 tetramerization, thus exposing the oligomerization-regulated nuclear export signal. | Alanine | tumor protein p53 | Homo sapiens |