Title : Susceptibility of amyloid beta peptide degrading enzymes to oxidative damage: a potential Alzheimer's disease spiral.

Pub. Date : 2005 Nov 22

PMID : 16285738






2 Functional Relationships(s)
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1 Insulysin (IDE) and neprilysin (NEP) were found to be inactivated by oxidation with hydrogen peroxide, an iron-ascorbate oxidation system, and by treatment with 2,2"-azobis(2-amidinopropane) dihydrochloride (AAPH). Iron insulin degrading enzyme Homo sapiens
2 Insulysin (IDE) and neprilysin (NEP) were found to be inactivated by oxidation with hydrogen peroxide, an iron-ascorbate oxidation system, and by treatment with 2,2"-azobis(2-amidinopropane) dihydrochloride (AAPH). Iron insulin degrading enzyme Homo sapiens