Title : Clinical experience with decitabine in North American patients with myelodysplastic syndrome.

Pub. Date : 2005 Dec

PMID : 16273408






1 Functional Relationships(s)
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1 5-Aza-2"-deoxycytidine (decitabine, DAC) is a nucleoside analog, which, at low doses, acts as a hypomethylating agent and is fivefold to tenfold more active than 5-azacytidine (azacitidine, Vidaza)--currently the only approved drug for treatment of myelodysplastic syndrome (MDS). Nucleosides arylacetamide deacetylase Homo sapiens