Title : Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants.

Pub. Date : 2006 Jan 27

PMID : 16272152






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 An hSERT mutant with single cysteine substitutions in TM1 and TM3 resulted in formation of a high affinity cadmium metal coordination site, suggesting proximity of these domains in the tertiary structure of SERT. Metals tropomyosin 3 Homo sapiens