Title : Triamcinolone acetonide destabilizes VEGF mRNA in Müller cells under continuous cobalt stimulation.

Pub. Date : 2005 Nov

PMID : 16249516






6 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Triamcinolone acetonide destabilizes VEGF mRNA in Muller cells under continuous cobalt stimulation. Cobalt vascular endothelial growth factor A Homo sapiens
2 VEGF mRNA decreased 50- to 100-fold 6 hours after treatment with TA and cobalt compared with cobalt alone. Cobalt vascular endothelial growth factor A Homo sapiens
3 VEGF mRNA decreased 50- to 100-fold 6 hours after treatment with TA and cobalt compared with cobalt alone. Cobalt vascular endothelial growth factor A Homo sapiens
4 VEGF mRNA stability was decreased in cobalt-stimulated, TA-treated cells compared with cobalt alone in cells synchronized by exposure to actinomycin D. Cobalt vascular endothelial growth factor A Homo sapiens
5 VEGF mRNA stability was decreased in cobalt-stimulated, TA-treated cells compared with cobalt alone in cells synchronized by exposure to actinomycin D. Cobalt vascular endothelial growth factor A Homo sapiens
6 CONCLUSIONS: TA may decrease VEGF synthesis by nongenomic destabilization of VEGF mRNA in cobalt-stimulated Muller cells. Cobalt vascular endothelial growth factor A Homo sapiens