Title : Cytotoxic effect of Shiga toxin-2 holotoxin and its B subunit on human renal tubular epithelial cells.

Pub. Date : 2006 Feb

PMID : 16242986






4 Functional Relationships(s)
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1 The purpose of the present study was to examine the cytotoxicity of Stx type 2 (Stx2 holotoxin) and its B subunit (Stx2 B subunit) on human renal tubular epithelial cells (HRTEC), in the presence and absence of inflammatory factors. stichoposide syntaxin 2 Homo sapiens
2 HRTEC are sensitive to both Stx2 holotoxin and Stx2 B subunit in a dose- and time-dependent manner. stichoposide syntaxin 2 Homo sapiens
3 The effects of Stx2 B subunit appear at doses higher than those used for Stx2 holotoxin. stichoposide syntaxin 2 Homo sapiens
4 The effects of Stx2 B subunit appear at doses higher than those used for Stx2 holotoxin. stichoposide syntaxin 2 Homo sapiens