Title : Rosmarinic acid inhibits angiogenesis and its mechanism of action in vitro.

Pub. Date : 2006 Aug 8

PMID : 16239062






2 Functional Relationships(s)
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1 RA also reduced intracellular reactive oxygen species (ROS) level, H2O2-dependent VEGF expression and IL-8 release of endothelial cells. rosmarinic acid C-X-C motif chemokine ligand 8 Homo sapiens
2 These findings suggested that the anti-angiogenic potential of RA might be related to its anti-oxidative activity, which further resulted in the inhibition of ROS-associated VEGF expression and IL-8 release. rosmarinic acid C-X-C motif chemokine ligand 8 Homo sapiens