Title : Sequence-specific DNA interstrand cross-linking by an aziridinomitosene in the absence of exogenous reductant.

Pub. Date : 2005 Oct 25

PMID : 16229487






1 Functional Relationships(s)
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1 Replacement of dG at 5"-d(CG) with 2"-deoxyinosine (dI), which lacks the exocyclic C2 amino group present in dG, also prevented DNA ICL formation by 4, revealing an essential role for the dG C2 amino group in the interstrand cross-linking reaction between 4 and duplex DNA. cysteinylglycine Glutamate Carrier 2 Drosophila melanogaster