Title : TGF-beta and TNF-alpha producing effects of losartan and amlodipine on human mononuclear cell culture.

Pub. Date : 2005 Oct

PMID : 16221098






3 Functional Relationships(s)
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1 TGF-beta and TNF-alpha producing effects of losartan and amlodipine on human mononuclear cell culture. Amlodipine transforming growth factor beta 1 Homo sapiens
2 RESULTS: Amlodipine was found to induce TGF-beta synthesis from mononuclear cells with increasing concentrations, while it was found to inhibit TNF-alpha secretion with increasing concentrations. Amlodipine transforming growth factor beta 1 Homo sapiens
3 CONCLUSION: Anti-atherosclerotic effects of amlodipine and losartan might be through increased secretion of TGF-beta from mononuclear cells. Amlodipine transforming growth factor beta 1 Homo sapiens