Title : Metabolic regulation of oocyte cell death through the CaMKII-mediated phosphorylation of caspase-2.

Pub. Date : 2005 Oct 7

PMID : 16213215






1 Functional Relationships(s)
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1 We show that pentose-phosphate-pathway generation of NADPH is critical for oocyte survival and that the target of this regulation is caspase-2, previously shown to be required for oocyte death in mice. Pentosephosphates 2,4-dienoyl CoA reductase 1, mitochondrial Mus musculus