Pub. Date : 2005 Oct
PMID : 16210060
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Prevention of IL-1 signaling attenuates airway hyperresponsiveness and inflammation in a murine model of toluene diisocyanate-induced asthma. | Toluene 2,4-Diisocyanate | interleukin 1 complex | Mus musculus |
| 2 | OBJECTIVE: We sought to determine the role of IL-1 signaling in airway reactivity and inflammation by using a murine model of TDI-induced asthma. | Toluene 2,4-Diisocyanate | interleukin 1 complex | Mus musculus |
| 3 | Prevention of IL-1 signaling through deletion of the IL-1 receptor type I or administration of neutralizing antibodies to both IL-1beta and IL-1alpha abrogated the development of TDI-induced asthma. | Toluene 2,4-Diisocyanate | interleukin 1 complex | Mus musculus |