Title : A comparison of cyclohexanone and tetrahydro-4H-thiopyran-4-one 1,1-dioxide as pharmacophores for the design of peptide-based inhibitors of the serine protease plasmin.

Pub. Date : 2005 Oct 14

PMID : 16209572






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Comparisons of the IC50 values of the three pairs show that the electron-withdrawing sulfone functional group is a beneficial element for the design of plasmin inhibitors. Sulfones plasminogen Homo sapiens