Title : Goniothalamin induces cell cycle-specific apoptosis by modulating the redox status in MDA-MB-231 cells.

Pub. Date : 2005 Oct 17

PMID : 16202990






2 Functional Relationships(s)
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1 The disruption of intracellular redox balance caused by goniothalamin was associated an enhancement of cdc25C degradation. goniothalamin cell division cycle 25C Homo sapiens
2 Taken together, our result demonstrates for the first time that goniothalamin disrupts intracellular redox balance and induces cdc25C degradation, which in turn causes cell cycle arrest and cell death maximally at G(2)/M phase in MDA-MB-231 cells. goniothalamin cell division cycle 25C Homo sapiens