Title : Signal transduction pathways and gating mechanisms of native TRP-like cation channels in vascular myocytes.

Pub. Date : 2006 Jan 1

PMID : 16195316






2 Functional Relationships(s)
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1 It is apparent that G-protein-coupled pathways linked to stimulation of phospholipase activity have a profound effect on regulating channel activity and that generation of diacylglycerol (DAG) is a central event in these signalling cascades with this triglyceride having a pivotal role in gating cation channels via both PKC-independent and -dependent mechanisms. Diglycerides proline rich transmembrane protein 2 Homo sapiens
2 It is apparent that G-protein-coupled pathways linked to stimulation of phospholipase activity have a profound effect on regulating channel activity and that generation of diacylglycerol (DAG) is a central event in these signalling cascades with this triglyceride having a pivotal role in gating cation channels via both PKC-independent and -dependent mechanisms. Diglycerides proline rich transmembrane protein 2 Homo sapiens